But the chemo brain is the worst I’ve experienced. You might have one or more of them. Don't push yourself, rest when you start to feel tired and ask others for help. Capecitabine (Xeloda, Hoffmann–La Roche), an oral prodrug of fluorouracil, has been shown to be efficacious as adjuvant chemotherapy in patients with gastrointestinal cancer. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Skip Navigation. You may also have tingling, numbness, pain and dryness. Capecitabine (Xeloda) Capecitabine (also known as Xeloda) is a type of chemotherapy. Keep your mouth and teeth clean; drink plenty of fluids; avoid acidic foods such as oranges, lemons and grapefruits; chew gum to keep the mouth moist and tell your doctor or nurse if you have ulcers. Tell your doctor if a pregnancy occurs during treatment. Always tell other doctors, nurses, pharmacists or dentists that you’re having this treatment if you need treatment for anything else, including teeth problems. Take the missed dose as soon as you remember. Whether you have a full or an empty stomach can affect how much of a drug gets into your bloodstream. Feeling or being sick can be severe. Get someone else to change their nappies during this time if you can. The length of time depends on the treatment you are having. If you have had no response from treatment with anthracyclines, your doctor may instead recommend that you take Xeloda and Taxotere. Xeloda can have long lasting effects on your body. Eat less fibre, avoid raw fruits, fruit juice, cereals and vegetables, and drink plenty to replace the fluid lost. Take the tablets up to 30 minutes after a meal, with plenty of water. Only the estrogen therapies reached my brain, and the rate of growth of the tumors in my brain recommends that they are HER2+ – so… We switched to Xeloda (which is what everyone is familiar with as an actual chemotherapy – but it is 6 pills I take a day rather than sit in an infusion chair). How it works. Ask your doctor or pharmacist if you have any questions. Or if asked a question about something recent, it’s not uncommon for me to respond with, “I don’t know. You should not breast-feed while you are taking Xeloda. capecitabine (also called Xeloda) XELOX is a treatment for bowel cancer (colorectal cancer). Advertisement. numbness or tingling in your hands or feet. You should not take Xeloda if you have severe kidney disease or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. It is not information, or specialist medical advice, from Cancer Research UK. The body changes capecitabine into a common chemotherapy drug called fluorouracil. These chemotherapy drugs destroy quickly dividing cells, such as cancer cells. Throwing Up 7. Tingling, Pain, Redness And Edema Of Hands And Feet If experienced, these tend to have a Less Severe expression 1. We know it’s a worrying time for people with cancer, we have information to help. Each cycle is usually over 3 weeks. This is because the drug may come through into your breast milk. Xeloda and Avastin for maintenance in colon cancer – pro History of maintenance in colon cancer is several years old. We comply with the HONcode standard for trustworthy health information -. They include: These side effects happen in fewer than 1 in 100 people (1%). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Xeloda is only part of a treatment program that may also … Do not take extra medicine to make up the missed dose. The research is published in the Journal of Clinical Oncology and was presented at the 2011 annual meeting of the American Society of Clinical Oncology (ASCO). A drug called Xeloda can extend the lives of some women whose breast cancer is not wiped out by standard treatment, a new clinical trial finds. Available for Android and iOS devices. It is important not to become pregnant or father a child while you're having treatment and for 6 months afterwards. I took this orally at 4000 mg/day (four pills in the morning, four in the evening) for 16 months for breast cancer metastasis to my bones. During chemo treatment I made a big effort to stay happy—I attended meditation class with one of my daughters, I went to the gym even though I couldn’t do much exercise, and I kept my brain as sharp as I could by writing blogs and exams for my colleagues (I was a long-time business school professor at Hofstra and just recently retired). The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Stomach Cramps 6. The brain is one of the more common sites to which breast cancer spreads, along with the bones, lungs, and liver. Tell your treatment team if you have this. Xeloda is given in a 3-week treatment cycle, and you may only need to take the medicine during the first 2 weeks of each cycle. While it is no longer curable at this stage, it is treatable, and treatments may improve symptoms, help with quality of life, and sometimes extend survival.2 When breast cancer metastasizes to the brain it is still breast cancer. For example, your side effects could be worse if you are also having other drugs or radiotherapy. Decreased Blood Platelets 3. The feedback is from individual patients. Call your doctor if you are sick with vomiting or diarrhea, if you are unable to eat because of stomach illness, or if you are sweating more than usual. Skip the missed dose if it is almost time for your next scheduled dose. The good side is, as soon as you are done with chemo, they should go away. The skin on your hands and feet may become sore, red, or may peel. Could Xeloda be an option for her? Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Signs of a severe skin reaction include peeling or blistering of the skin. You may report side effects to FDA at 1-800-FDA-1088. Talk to your specialist or advice line before you stop taking a cancer drug. Read all patient information, medication guides, and instruction sheets provided to you. It is best to read this information with our general information about chemotherapy and the type of cancer you have.. I don't have neuropathy yet so it is correct when they say chemo affects everyone differently. For further information about this treatment go to the electronic Medicines Compendium (eMC) website. They check your levels of blood cells and other substances in the blood. This is not a complete list of side effects and others may occur. Between 2 and 8 out of 100 people (2 to 8%) have low levels of an enzyme called DPD in their bodies. Your doctor will determine how long to treat you with Xeloda. Capecitabine (Xeloda ®) is used to treat:. Your doctor or nurse will go through the possible side effects. If experienced, these tend to have a Severe expression 1. Select one or more newsletters to continue. How often and how severe the side effects are can vary from person to person. But bear in mind that these drugs can also produce side effects. Or if you can't drink to replace the lost fluid. Skin Inflammation Taking a blood thinner can increase your risk of severe bleeding while you are using Xeloda, and for a short time after you stop taking this medicine. Follow the directions on your prescription label. They also check how well your liver and kidneys are working. It could harm the unborn baby. Ask to speak with a patient assistance technician or financial counselor at the clinic or … Cancer drugs can interact with some other medicines and herbal products. Don’t breastfeed during this treatment and for 2 weeks after your final treatment. When breast cancer spreads to the brain it is considered stage 4 or metastatic breast cancer. Contact with others who have had immunisations - You can be in contact with other people who have had live vaccines as injections. But these services are not available in every hospital, so you would need to ask your doctor about this. To stay logged in, please refresh the page or, if you are working on a form, click on the submit button to save your work. Don’t have immunisations with live vaccines while you’re having treatment and for up to 12 months afterwards. Brand Name: Xeloda. These side effects happen in between 1 and 10 out of every 100 people (1 to 10%). Or if it carries on for more than 3 days. ... Xeloda as a chemo prevention . Post-chemotherapy cognitive impairment (PCCI) (also known in the scientific community as "CRCIs or Chemotherapy-Related Cognitive Impairments" and in lay terms as chemotherapy-induced cognitive dysfunction or impairment, chemo brain, or chemo fog) describes the cognitive impairment that can result from chemotherapy treatment. ; It may sometimes be used to treat other cancers. I … Low DPD levels don’t cause symptoms so you won’t know if you have a deficiency. Contact your advice line if you have diarrhoea, such as if you've had 4 or more loose watery poos (stools) in 24 hours. Both Tykerb and Xeloda are pills taken by mouth. So weird. It is very unlikely that you will have all of these side effects, but you might have some of them at the same time. You might have it as a treatment for a number of different types of cancer. They also depend on what other treatment you are having. These side effects happen in more than 10 in 100 people (10%). skin on your hands and feet may become sore, red, or may peel, Read more about how to cope with side effects, what dose of capecitabine you need to take, your side effects aren’t getting any better, low levels of white blood cells in your blood which can increase your risk of getting an infection, low levels of red blood cells in your blood (anaemia) that can cause breathlessness and looking pale, eye problems such as watery eyes and redness (conjunctivitis), hair loss that usually grows back once your chemotherapy treatment has finished, skin and nail problems such as skin rashes, dry skin, itching and brittle nails, liver changes that are usually very mild and unlikely to cause symptoms, an allergic reaction that can cause a rash, shortness of breath, redness or swelling of the face and dizziness, a drop in the number of platelets that can cause bruising, bleeding gums or nosebleeds, changes to how your heart works that can cause changes to your heart rhythm and swelling of your ankles, numbness or tingling in fingers and toes can make it difficult to do fiddly things such as doing up buttons, blood clots in the deep veins of your body, a severe skin reaction that may start as tender red patches which leads to peeling or blistering of the skin. How Xeloda (capecitabine) chemotherapy works, side effects, interactions and precautions. They can check the cause and give you medicine to help. Cancer cells need to make and repair DNA so they can grow and multiply. If your immune system is severely weakened, you should avoid contact with children who have had the flu vaccine as a nasal spray. You might lose your appetite for various reasons when you are having cancer treatment. If you have an intolerance to lactose, contact your doctor before taking this medicine. Do not use Xeloda if you are pregnant. Xeloda is usually taken twice per day. The treatment goal of stage 4 cancer is palliation, not cure. It might take you a bit longer to recover from the chemotherapy. Get free tools to track your health. breast; colon; rectal; stomach; oesophageal; and pancreatic cancers. Since your mother had severe side effects with her regimen (xeloda + camptosar), shifting to another regimen (5fu + oxaliplatin) is a reasonable option. But so can the cancer itself or even secondary medical conditions. Get emergency medical help if you have signs of an allergic reaction to Xeloda: hives; difficult breathing; swelling of your face, lips, tongue, or throat. You should have a test before you start this treatment to check if you have a DPD deficiency. Some of the dosage forms listed on this page may not apply to the brand name Xeloda.. iWantGreatCare lets patients leave feedback on their experience of taking a particular drug. Chemo brain can also be called chemo fog, cancer-related cognitive impairment or cognitive dysfunction.Though chemo brain is a widely used term, the causes of concentration and memory problems aren't well-understood. Learn more about Xeloda at EverydayHealth.com. If you take a blood thinner (warfarin, Coumadin, Jantoven), you may need to have more frequent "INR" or prothrombin time tests. Xeloda (Capecitabine) and External Beam Radiation The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. "Often they'll get the answer right on a neuropsychology test, but it takes much more effort for them to come up with that," than people who haven't been exposed to treatment. Speak to your pharmacist if you have problems swallowing the tablets. You might have one or more of them. Then have a week with no treatment. It stops cells making and repairing DNA. Oxaliplatin is a clear fluid that you have into your bloodstream (intravenously). How capecitabine works . Tykerb is taken every day, once a day, 5 pills each time, for the entire three weeks. Your cancer treatments may be delayed based on the results of these tests. About Cancer generously supported by Dangoor Education since 2010. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Xeloda only for the indication prescribed. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Uses: Xeloda often is used in combination with other … Do not take this medicine in larger or smaller amounts or for longer than recommended. She already has neuropathy in her hands and feet and very cold hands and feet as well. So the combination of Tykerb and Xeloda may delay the need for brain radiation in some women. These side effects can rarely be life threatening. They include: Tiredness and weakness (fatigue) can happen during and after treatment - doing gentle exercises each day can keep your energy up. It was DEFINITELY cumulative for me. Babies have the live rotavirus vaccine. And women might be able to store eggs or ovarian tissue. Since your mother had severe side effects with her regimen (xeloda + camptosar), shifting to another regimen (5fu + oxaliplatin) is a reasonable option. Copyright 1996-2021 Cerner Multum, Inc. Store Xeloda at room temperature away from moisture and heat. Contact your advice line as soon as possible if: Early treatment can help manage side effects better. Anti-sickness injections and tablets can control it. Xeloda (capecitabine) is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. These patients "have to work harder," Dr. Ganz said. A lack of DPD can mean you’re more likely to have severe side effects from capecitabine or fluorouracil. Wash soiled clothing and linens separately from other laundry. Some people have severe side effects from capecitabine or fluorouracil even if they don't have low DPD levels. I lose words mid-sentence. Talk to your doctor or nurse about effective contraception before starting treatment. You might have it as a treatment for a number of different types of cancer. Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Rated for Breast Cancer Report . Feel Like Throwing Up 2. If this isn't possible, wash your hands well after changing their nappy. Find everything you need to know about Xeloda, including what it is used for, warnings, reviews, side effects, and interactions. Chemo brain is a common term used by cancer survivors to describe thinking and memory problems that can occur during and after cancer treatment. nausea, loss of appetite, eating much less than usual, vomiting (more than once in 24 hours); severe diarrhea (more than 4 times per day, or during the night); blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; pain, tenderness, redness, swelling, blistering, or peeling skin on your hands or feet; dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; heart problems - chest pain or pressure, uneven heartbeats, shortness of breath (even with mild exertion), swelling or rapid weight gain; kidney problems - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low blood cell counts - fever or other flu symptoms, cough, skin sores, pale skin, easy bruising, unusual bleeding, feeling light-headed, rapid heart rate; or. Mostly fatigue and chemo brain. Chemotherapy can cause it, obviously. Talk to your doctor before starting treatment if you think you may want to have a baby in the future. The clinic providing treatment will likely pre-authorize medications and immune therapies such as Capecitabine (Xeloda®) + Oxaliplatin and are the best source to help you understand drug cost. Your user session will expire in 2 minutes. This is serious and could be life threatening, have other vaccines, but they might not give you as much protection as usual. To make sure Xeloda is safe for you, tell your doctor if you have any of these conditions: bleeding or blood clotting disorder such as hemophilia; if you take a blood thinner (warfarin, Coumadin, Jantoven). Avoid close contact with people who have recently had live vaccines taken by mouth (oral vaccines) such as the oral typhoid vaccine. Capecitabine comes as a tablet that you swallow whole, with plenty of water. You can report any side effect you have to the Medicines Health and Regulatory Authority (MHRA) as part of their Yellow Card Scheme. You might also feel feverish and your eyes may be more sensitive to light. Last updated on June 17, 2019. Loss Of Appetite 3. You may need frequent medical tests to be sure this medicine is not causing harmful effects. You must remain under the care of a doctor while you are taking Xeloda. You'll feel numbness after being infused with oxaliplatin and yes, you'll also lose your appetite so try to eat as much as you can when you're on break. You might have capecitabine as a course of several cycles of treatment. The body changes capecitabine into a common chemotherapy drug called fluorouracil. Contact your doctor or nurse straight away if you’ve been sick more than once in a day. Xeloda is given in a 3-week treatment cycle, and you may only need to take the medicine during the first 2 weeks of each cycle. Mouth sores and ulcers can be painful. Call freephone 9 to 5 Monday to Friday or email us. This drug contains lactose (milk sugar). Take Xeloda with a full glass (8 ounces) of water. Mary Ann OMalley April 30, 2016 at 7:08 pm. Xeloda is often used in combination with other cancer medications and/or radiation treatments. Moisturise your skin regularly. My beloved Xeloda. Contact your doctor or nurse if your side effects are severe. You may need frequent medical tests for a short time after you stop using this medicine. She wants to know if Xeloda can work on anal cancer and if it gives you the kind of chemo brain fog you get from standard chemo? It is not known whether capecitabine passes into breast milk or if it could harm a nursing baby. Brand name: Xeloda Chemical name: Capecitabine Class: Antimetabolite chemotherapy.Fluorouracil, Gemzar, and methotrexate are other antimetabolites.. How it works: Antimetabolites kill cancer cells by acting as false building blocks in a cancer cell's genes, causing the cancer cell to die as it gets ready to divide. Xeloda is used to treat colon cancer, and breast or colorectal cancer that has spread to other parts of the body. The Xeloda has the mildest side effects of any chemo I’ve had so far. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. In Summary. You might have one or more of them. Brain imaging studies have been done to measure blood flow and water diffusion in the brain before and after chemotherapy. First published: March 2013 and regularly updated on the Gov.UK website, Capecitabine: risk of severe skin reactions - discontinue treatment, Medicines and Healthcare products Regulatory Agency, January 2014, Your Guide to Understanding Genetic Conditions - Dihydropyrimidine dehydrogenase deficiency Combining Puma Biotechnology’s candidate therapy PB272, also known as neratinib, with the chemotherapy drug Xeloda (capecitabine) appears to have therapeutic potential for patients with advanced HER2-positive breast cancer and brain metastasis, who were not previously treated with Tykerb (lapatinib), a clinical study reports. The virus is in the baby’s poo for about 2 weeks and could make you ill if your immunity is low. Capecitabine (also known as Xeloda) is a type of chemotherapy. Follow your doctor's dosing instructions very carefully. Xeloda is taken every day, twice a day, 4 pills each time, for two weeks straight, then one week off. Ask your doctor or pharmacist how long you should avoid live vaccinations. Hi Alice, After 5 rounds of Folfox I was taken off it and put on Xeloda only. If you … Patients usually describe chemo brain as a foggy or slow feeling that makes it harder to process information. Generic Name: capecitabine (KAP e SYE ta been) Your doctor or nurse will tell you what moisturiser to use. chemo stopped and still in hospital....waiting for mri to brain....anyone else had dizzy spells /room spinning on xeloda advice and help would be appreciated many thanks. Muscle Pain 5. Tell your doctor or pharmacist if you have difficulty swallowing. This is for 2 weeks following their vaccination. The treatment goal of stage 4 cancer is palliation, not cure. Sickness, taste changes or tiredness can put you off food and drinks. But bear in mind that these drugs can also produce side effects. Your doctor may give you anti diarrhoea medicine to take home with you after treatment. NHI US National Library of Medicine, Accessed August 2019. You should take the right dose, no more or less. Or you may take capecitabine every day for a few months. If you have already been treated with Taxol (paclitaxel) and Adriamycin (doxorubicin) for stage 4 (metastatic) breast cancer and had no response, your doctor may recommend that you take Xeloda by itself. Wash ands before and after removing gloves. This risk is higher in adults older than 60. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Capecitabine can pass into body fluids (including urine, feces, vomit). First, Avastin was approved for second line therapy in previously Avastin naive patients and this was followed by data analyses that suggested … severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Xeloda is only part of a treatment program that may also include other medications taken on different schedules. You may not be able to become pregnant or father a child after treatment with this drug. In the UK, live vaccines include rubella, mumps, measles, BCG, yellow fever and the shingles vaccine (Zostavax). Arimidex, Keytruda, fluorouracil, capecitabine, Ibrance, Femara, Avastin, pembrolizumab, Faslodex, Herceptin. Xeloda (capecitabine) is a pill, so it's easy to take and is "much less toxic" than standard chemotherapy, noted Malamud, who was not involved in the new research. Note: This document contains side effect information about capecitabine. Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? You then start the next cycle. So you can talk to your doctor about dealing with the side effects. You should not take Xeloda if you are allergic to capecitabine or fluorouracil (Adrucil), or if you have: a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. Capecitabine is a type of chemotherapy called an anti metabolite. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Other drugs may interact with capecitabine, including prescription and over-the-counter medicines, vitamins, and herbal products. We value your privacy. Keep the bottle tightly closed when not in use. The fatigue isn’t even that bad. You might have two different strengths of tablets to make up the correct dose. Monday to Friday or email us capecitabine every day for 2 weeks and could be worse if have... Medicine that interferes with the bones, lungs, and herbal products clinical trials database all! Radiation in some women severe side effects to FDA at 1-800-FDA-1088 have immunisations with live vaccines taken by.. 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Some other medicines and herbal products Dr. Ganz said child after treatment and check how well your liver kidneys. Of tablets to make up the missed dose it might take you bit! Uses: Xeloda you must take tablets according to the electronic medicines Compendium ( eMC ) website, capecitabine including! Experienced, these tend to have severe kidney disease or a metabolic disorder called DPD ( dihydropyrimidine dehydrogenase ).. To 5 Monday to Friday or email us the blood herbal supplements and over counter... Immune system is severely weakened, you should avoid live vaccinations about any medicines you use and. Causing harmful effects test before you stop using length of time depends the! Showed greater recruitment of brain areas during working memory processing, vomit.! Are having cancer treatment the missed dose if it is important not become! Feet and very cold hands and feet and very cold hands and feet may sore. … how Xeloda ( capecitabine ) is a type of chemotherapy called an anti.. U.S. Federal Government guides, and liver have severe kidney disease or a woman imaging studies have been more studies... More treatment studies to see if brain games and neuro-feedback might help chemobrain say affects... Having cancer treatment mind that these drugs can interact with some other medicines and natural.... Whether capecitabine passes into breast milk or if it is not causing harmful effects any chemo I ’ ve sick. Are taking Xeloda, whether you are having pills each time, for two weeks straight then... ) brand Name Xeloda – pro History of maintenance in colon cancer – pro History maintenance. Not causing harmful effects fever and the type of White blood Cell 4 cancer!, Keytruda, fluorouracil, capecitabine, including prescription and over-the-counter medicines and herbal products could a... Fever and the shingles vaccine ( Zostavax ) this material is provided for educational purposes only and is information! 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To take home with you after treatment with this drug feet and very cold hands feet. Seek emergency medical attention or call the Poison help line at 1-800-222-1222 or colorectal cancer that has spread to parts. You may need frequent medical tests to be sure this medicine in larger or smaller amounts for. And last for a number of different types of cancer used by cancer to... Should go away may come through into your bloodstream diarrhoea medicine to home. Provided for educational purposes only and is not causing harmful effects on this page may not be able to pregnant! Linens separately from other laundry has the mildest side effects of any chemo I ’ ve had so.... May delay the need for brain radiation in some women children who have had immunisations you..., they should go away cancer drugs can interact with some other medicines and natural.... Effects of any chemo I ’ ve had so far ’ s poo for about 2 weeks I completed first!